2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE)
2-fluoro-3-methylpyridine
CAS: 2369-18-8
Molecular Formula: C6H6FN
2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE) - Names and Identifiers
| Name | 2-fluoro-3-methylpyridine |
| Synonyms | 2-Fluoro-3-picoline 2-FLUORO-3-PICOLINE 2-fluoro-3-methypyridine 2-fluoro-3-methylpyridine 2-FLUORO-3-METHYLPYRIDINE 2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE) |
| CAS | 2369-18-8 |
| EINECS | 624-901-9 |
| InChI | InChI=1/C6H3Br2F/c7-5-2-1-4(9)3-6(5)8/h1-3H |
2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE) - Physico-chemical Properties
| Molecular Formula | C6H6FN |
| Molar Mass | 111.12 |
| Density | 1.098 g/mL at 25 °C (lit.) |
| Boling Point | 154-155 °C (lit.) |
| Flash Point | 119°F |
| Vapor Presure | 0.174mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.098 |
| Color | Colorless to Light orange to Yellow |
| BRN | 1877 |
| pKa | -0.14±0.10(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | n20/D 1.476(lit.) |
| Physical and Chemical Properties | Colorless transparent liquid |
2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE) - Risk and Safety
| Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R1020/21/2236/37/38 - |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S16 - Keep away from sources of ignition. S16 26 36/37/39 - |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | IRRITANT, FLAMMABLE |
| Packing Group | Ⅲ |
2-FLUORO-3-METHYLPYRIDINE (2-FLUORO-3-PICOLINE) - Introduction
2-fluoro-3-methylpyrridine (2-fluoro-3-methylpyrridine) is an organic compound with the chemical formula C6H6FN.
Nature:
2-fluoro-3-methylpyridine is a colorless liquid with a pungent odor. It is volatile at room temperature and soluble in organic solvents such as ethanol and ether. It has a melting point of -31°C and a boiling point of 129°C.
Use:
2-fluoro-3-methylpyridine has a wide range of applications in organic synthesis. It is an intermediate of many important compounds and can be used to prepare various drugs, pesticides and functional materials.
Method:
The preparation of 2-fluoro-3-methylpyriridine is generally obtained by reacting pyridine with fluorine gas. In a specific step, pyridine and fluorine gas are reacted with a catalyst under suitable reaction conditions to obtain 2-fluoro-3-methylpyriridine.
Safety Information:
2-fluoro-3-methylpyridine is an irritant and may cause irritation to the eyes, skin, and respiratory system. During use, care should be taken to avoid contact with skin and eyes, and maintain good ventilation conditions. During handling and storage, the relevant safe operation procedures should be followed to avoid exposure to fire and high temperature environment. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
Nature:
2-fluoro-3-methylpyridine is a colorless liquid with a pungent odor. It is volatile at room temperature and soluble in organic solvents such as ethanol and ether. It has a melting point of -31°C and a boiling point of 129°C.
Use:
2-fluoro-3-methylpyridine has a wide range of applications in organic synthesis. It is an intermediate of many important compounds and can be used to prepare various drugs, pesticides and functional materials.
Method:
The preparation of 2-fluoro-3-methylpyriridine is generally obtained by reacting pyridine with fluorine gas. In a specific step, pyridine and fluorine gas are reacted with a catalyst under suitable reaction conditions to obtain 2-fluoro-3-methylpyriridine.
Safety Information:
2-fluoro-3-methylpyridine is an irritant and may cause irritation to the eyes, skin, and respiratory system. During use, care should be taken to avoid contact with skin and eyes, and maintain good ventilation conditions. During handling and storage, the relevant safe operation procedures should be followed to avoid exposure to fire and high temperature environment. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
Last Update：2024-04-09 02:00:44
